A single-arm phase 2 study of abemaciclib in adult patients with recurrent grade 3 oligodendroglioma.
Wills CA; Mohan S; Nabavizadeh A; Patel T; Prior T; Mansour M; McCoy E; Shah S · 2025 · Neuro-oncology advances
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Novel treatments are needed for oligodendroglioma that has recurred following radiotherapy (RT) and chemotherapy. The cyclin D1-CDK4 axis is frequently dysregulated in oligodendroglioma. Abemaciclib is a selective CDK4/6…
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Metadata source: Europe PMC · DOI 10.1093/noajnl/vdaf011