e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine

Effects of an orexin receptor 2-selective agonist on salivary secretion in rats.

Ichishima J; Nakakariya M; Kimura H · 2026 · Scientific reports

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Narcolepsy type 1 (NT1) is caused by a significant loss of orexin-producing neurons. In clinical trials, multiple orexin receptor 2 (OX2R)-selective agonists (e.g., danavorexton, TAK-994, and oveporexton) improved wakefulness and decreased…

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Metadata source: Europe PMC · DOI 10.1038/s41598-026-44080-9