TLE3,a transcriptional co-repressor, is dispensable for spermatogenesis and male fertility in mice.
Zhao; Xu; Zhou; Yu; Liu; Zhou; Ke; Sun · 2026 · Theriogenology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
As a member of the Groucho/TLE family, Transducin-like enhancer of split 3 (TLE3) functions as a transcriptional co-repressor that is highly expressed in the testis. It recruits histone deacetylases (HDACs) and binds histones to mediate…
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Metadata source: PubMed · DOI 10.1016/j.theriogenology.2026.118035