Oxidative DNA Damage as an Integrative Marker of Redox Dysfunction Associated with Doxorubicin-Induced Cardiotoxicity in Pediatric Leukemia.
Gándara-Mireles JA; Reyes Espinoza EA; Loera-Castañeda V; Córdova Hurtado LP; González Font AE; Grijalva Ávila JC; Villanueva Fierro I; Lares-Asseff I · 2026 · Current issues in molecular biology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Doxorubicin (Dox) is a cornerstone in the treatment of pediatric acute lymphoblastic leukemia (ALL), but its use is limited by dose-dependent cardiotoxicity. Oxidative stress, arising from mitochondrial dysfunction, enzymatic generation of…
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Metadata source: Europe PMC · DOI 10.3390/cimb48060577