The emergence of inflammatory microglia during gut inflammation is not affected by FFAR2 expression in intestinal epithelial cells or peripheral myeloid cells.
Caetano-Silva ME; Rund L; Vailati-Riboni M; Matt S; Soto-Diaz K; Beever J; Allen JM; Woods JA · 2024 · Brain, behavior, and immunity
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Gut inflammation can trigger neuroinflammation and is linked to mood disorders. Microbiota-derived short-chain fatty acids (SCFAs) can modulate microglia, yet the mechanism remains elusive. Since microglia do not express free-fatty acid…
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Metadata source: Europe PMC · DOI 10.1016/j.bbi.2024.03.016