Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites
Emily E. Fay; Lindsay C. Czuba; Jennifer E. Sager; Sara Shum; Alyssa Stephenson-Famy; Nina Isoherranen · 2021 · Therapeutic Drug Monitoring
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background: Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP…
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Metadata source: Crossref · DOI 10.1097/ftd.0000000000000885