e-ISSN: Pending
Replication FailureMedicine

Plasma short-chain fatty acids are associated with COPD and COPD phenotypes.

Rotevatn AØ; Eagan TM; McCann A; Laupsa-Borge J; Tangedal S; Husebø GR; Nielsen R · 2026 · BMC pulmonary medicine

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Background and aim Short-chain fatty acids (SCFAs) are metabolites largely produced by the gut microbiota, except for formate, which is also produced by the host. SCFAs may influence COPD development by modulating the immune system. This…

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Metadata source: Europe PMC · DOI 10.1186/s12890-026-04348-2