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Negative / Null Result ReportOpen accessMedicine· cited by 135

Transcranial Low-Level Laser Therapy Improves Neurological Performance in Traumatic Brain Injury in Mice: Effect of Treatment Repetition Regimen

Weijun Xuan; Fatma Vatansever; Liyi Huang; Qiuhe Wu; Yi Xuan; Tianhong Dai; Takahiro Ando; Tao Xu · 2013 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Low-level laser (light) therapy (LLLT) has been clinically applied around the world for a spectrum of disorders requiring healing, regeneration and prevention of tissue death. One area that is attracting growing interest in this scope is the use of transcranial LLLT to treat stroke and traumatic brain injury (TBI). We developed a mouse model of severe TBI induced by controlled cortical impact and explored the effect of different treatment schedules. Adult male BALB/c mice were divided into 3 broad groups (a) sham-TBI sham-treatment, (b) real-TBI sham-treatment, and (c) real-TBI active-treatmen

Abstract by Weijun Xuan; Fatma Vatansever; Liyi Huang; Qiuhe Wu; Yi Xuan; Tianhong Dai; Takahiro Ando; Tao Xu, PLoS ONE (2013) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0053454