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Negative / Null Result ReportOpen accessNeuroscience· cited by 10

Pharmacological Interventions in Autism Spectrum Disorder: A Comprehensive Review of Mechanisms and Efficacy

Eva Sclabassi; Sophie Peret; Chunqi Qian; Yuen Gao · 2025 · Biomedicines

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background and Objectives: Autism spectrum disorder (ASD) is a heterogeneous neuro-developmental condition characterized by social communication deficits, restricted interests, and repetitive behaviors. Pharmacological management is challenging given the complex neurobiology and frequent comorbidities. This review summarizes the current evidence for pharmacological treatments in ASD, highlighting efficacy, mechanisms, limitations, and emerging therapeutic targets. Methods: A comprehensive literature review was conducted across PubMed, Cochrane Library, and Embase to identify clinical trials, s

Abstract by Eva Sclabassi; Sophie Peret; Chunqi Qian; Yuen Gao, Biomedicines (2025) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.3390/biomedicines13123025