Aβ plaques do not protect against HSV‐1 infection in a mouse model of familial Alzheimer's disease, and HSV‐1 does not induce Aβ pathology in a model of late onset Alzheimer's disease
Olga V. Bocharova; Aidan Fisher; Narayan Pandit; Kara Molesworth; Olga Mychko; Alison Scott; Natallia Makarava; Rodney M. Ritzel · 2022 · Brain Pathology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
The possibility that the etiology of late onset Alzheimer's disease is linked to viral infections of the CNS has been actively debated in recent years. According to the antiviral protection hypothesis, viral pathogens trigger aggregation…
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Metadata source: OpenAlex · DOI 10.1111/bpa.13116