Lack of Association of the PLD4 SNP rs2841277 With Systemic Sclerosis in a US Caucasian population
Ma Y; Mayes MD; Guo X; Assassi S; Zhou X · 2024 · Preprint
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Abstract Objective This study aimed to examine whether a reported SSc-associated SNP rs2841277 in the PLD4 gene identified in an Asian population was also associated with SSc in US Caucasians. Methods The US Caucasian cohort consisting of…
Excerpt shown for reference under fair use — read the full paper at the publisher.
Hosted by the publisher — may require access.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Assessing the Effect of Visualizations on Bayesian Reasoning through Crowdsourcing
Replication FailureThe psychometric function: The lapse rate revisited
Replication FailurePriming, Replication, and the Hardest Science
Replication FailureOn gender and philosophical intuition: Failure of replication and other negative results
Replication FailureInvestigating Variation in Replicability
Replication FailureReplication of “Experiencing Physical Warmth Promotes Interpersonal Warmth” by
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: Europe PMC · DOI 10.21203/rs.3.rs-4238970/v1