Diagnostic Performance of the α-Synuclein Seed Amplification Assay for Dementia With Lewy Bodies: A Comparison Across 4 Laboratories.
Kumar R; Gravett S; Jelic V; Lange J; Oftedal L; Ciullini A; Bacınoğlu MB; De Luca CMG · 2026 · Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background and objectives The α-synuclein (α-syn) seed amplification assay (SAA) has shown promising results for diagnosing dementia with Lewy bodies (DLB) using CSF samples. A barrier to implementing α-syn SAA clinically is the use of…
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Metadata source: Europe PMC · DOI 10.1212/wnl.0000000000214614