Negative / Null Result ReportOpen accessMedicine

In vitro evaluation of the effect of galectins on Schistosoma mansoni motility

Tomoharu Takeuchi; Risa Nakamura; Megumi Hamasaki; Midori Oyama; Shinjiro Hamano; Tomomi Hatanaka · 2023 · BMC Research Notes

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Abstract Objective Galectins are sugar-binding proteins that participate in many biological processes, such as immunity, by regulating host immune cells and their direct interaction with pathogens. They are involved in mediating infection by Schistosoma mansoni, a parasitic trematode that causes schistosomiasis. However, their direct effects on schistosomes have not been investigated. Results We found that galectin-2 recognizes S. mansoni glycoconjugates and investigated whether galectin-1, 2, and 3 can directly affect S. mansoni in vitro. Adult S. mansoni were treated with recombinant galecti

Abstract by Tomoharu Takeuchi; Risa Nakamura; Megumi Hamasaki; Midori Oyama; Shinjiro Hamano; Tomomi Hatanaka, BMC Research Notes (2023) — licensed CC BY 4.0.

Read the full paper (open access)