Association of eosinophil major basic protein with intraocular lens dislocation in atopic dermatitis
Koji Komatsu; Yoichiro Masuda; Hoshiho Kubota; Ai Iwauchi; Masanobu Iida; Kosuke Ichihara; Euido Nishijima; Naoki Yamamoto · 2025 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract The study aimed to investigate whether eosinophil major basic protein (MBP), which is linked to cataract formation due to lens epithelial cell (LEC) damage in atopic dermatitis (AD), is associated with intraocular lens (IOL) dislocation. This retrospective observational study was conducted at a Medical University Hospital and included 22 eyes (10 AD, 12 non-AD [NAD]) that underwent IOL explantation and fixation. Surgeries were conducted to extract the intraocular lens capsule for morphological evaluations. Quantitative analysis of the MBP staining was conducted using the staining area
Abstract by Koji Komatsu; Yoichiro Masuda; Hoshiho Kubota; Ai Iwauchi; Masanobu Iida; Kosuke Ichihara; Euido Nishijima; Naoki Yamamoto, Scientific Reports (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1038/s41598-025-02083-y