e-ISSN: Pending
Replication FailureOpen accessMedicine· cited by 12

Pivotal results of SELECT-MDS-1 phase 3 study of tamibarotene with azacitidine in newly diagnosed higher-risk MDS

Amy Elizabeth Dezern; Sylvain Thépot; Stéphane de Botton; Andrea Patriarca; Dries Deeren; José Miguel Torregrosa Diaz; Giovanni Marconi; Teresa Bernal · 2025 · Blood Advances

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

ABSTRACT: Higher-risk myelodysplastic syndrome (HR-MDS) with RARA gene overexpression is a subset of patients (pts) with an actionable target for tamibarotene, an oral and a selective retinoic acid receptor-α (RAR-α) agonist. Tamibarotene…

Excerpt shown for reference under fair use — read the full paper at the publisher.

About to run something similar?

Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.

WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.

Metadata source: OpenAlex · DOI 10.1182/bloodadvances.2025016229