Multi-region brain transcriptomes uncover two subtypes of aging individuals with differences in Alzheimer risk and the impact of APOEε4
Annie Lee; Yiyi Ma; Lei Yu; Robert J. Dawe; Cristin Aubin; Konstantinos Arfanakis; Richard P Mayeux; David A. A Bennett · 2026 · iScience
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Abstract The heterogeneity of the older population suggests the existence of subsets of individuals which share certain brain molecular features and respond differently to risk factors for Alzheimer’s disease, but this population structure…
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Metadata source: OpenAlex · DOI 10.1016/j.isci.2026.117038