A phase 2 randomized, double-blind, placebo-controlled, proof-of-concept study of oral seletalisib in primary Sjögren’s syndrome
Maria Juárez; Nieves Díaz; Geoffrey I. Johnston; Saba Nayar; Andrew Payne; Eric Helmer; Dionne Cain; Paulette Williams · 2020 · Lara D. Veeken
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVES: This phase 2 proof-of-concept study (NCT02610543) assessed efficacy, safety and effects on salivary gland inflammation of seletalisib, a potent and selective PI3Kδ inhibitor, in patients with moderate-to-severe primary…
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Metadata source: OpenAlex · DOI 10.1093/rheumatology/keaa410