e-ISSN: Pending
Negative / Null Result ReportMedicine

Atezolizumab with carboplatin plus nab-paclitaxel combination therapy for advanced nonsquamous non-small cell lung cancer with impaired renal function: A multicenter, single-arm phase 2 trial (RESTART, LOGiK 2002).

Shiraishi Y; Shimose T; Tobino K; Toi Y; Wakuda K; Matsumoto H; Sakaguchi T; Mashimoto A · 2025 · Lung cancer (Amsterdam, Netherlands)

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Background The current standard of care for advanced non-small cell lung cancer (NSCLC) without driver oncogenes is platinum-based chemotherapy together with immune checkpoint inhibition. However, most phase 3 trials of such combination…

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Metadata source: Europe PMC · DOI 10.1016/j.lungcan.2025.108543