Effects of Janus kinase inhibition and interleukin 6 inhibition on serum cytokine/chemokine in idiopathic multicentric Castleman disease.
Fukui S; Sumiyoshi R; Koga T; Hosogaya N; Narita S; Morimoto S; Kamisawa O; Kiya R · 2026 · Drug discoveries & therapeutics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disease characterized by systemic inflammation. Although IL-6 receptor blockade with tocilizumab is an established treatment, Janus kinase (JAK) inhibition may…
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Metadata source: Europe PMC · DOI 10.5582/ddt.2026.01000