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Short NoteOpen accessMedicine

Oxidative stress and heart failure

Camelia C. Diaconu · 2019 · Archives of the Balkan Medical Union

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Abstract

Oxidative stress is involved in the pathophysiology of many chronic diseases, including heart failure. Oxidative stress is an imbalance between the production of reactive oxygen species (ROS) and the antioxidant defense. The overproduction of ROS can lead to cellular damage and eventually cellular death. This applies also in patients with chronic heart failure, who present a dramatic increase of oxidative stress associated with a pronounced decrease of the antioxidant defense mechanisms. The components of the antioxidant defense mechanism of myocardial cells are superoxide dismutase (SOD), cat

Abstract by Camelia C. Diaconu, Archives of the Balkan Medical Union (2019) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI https://doi.org/10.31688/abmu.2019.54.2.219