The RNA-binding protein CPEB1 marks healthy adult β cells in mice but is dispensable for β cell identity and function.
Nimkulrat SD; Wagner MR; Waters BJ; Pintozzi NG; Mendoza Niemes MDC; Sethna CR; Jayaraaman H; Blum B · 2025 · Scientific reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
RNA binding proteins (RBPs) are increasingly being recognized as important regulators of pancreatic β cells' identity and function. We identified the poly-A binding RBP, CPEB1, as a potential new regulator linked to β cell failure in…
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Metadata source: Europe PMC · DOI 10.1038/s41598-025-32403-1