Corneal dendritic cells and the subbasal nerve plexus following neurotoxic treatment with oxaliplatin or paclitaxel
Jeremy Chung Bo Chiang; David Goldstein; Azadeh Tavakoli; Terry Trinh; Jacob Klisser; Craig R. Lewis; Michael Friedlander; Thomas J. Naduvilath · 2021 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Immune cell infiltration has been implicated in neurotoxic chemotherapy for cancer treatment. However, our understanding of immune processes is still incomplete and current methods of observing immune cells are time consuming or invasive. Corneal dendritic cells are potent antigen-presenting cells and can be imaged with in-vivo corneal confocal microscopy. Corneal dendritic cell densities and nerve parameters in patients treated with neurotoxic chemotherapy were investigated. Patients treated for cancer with oxaliplatin (n = 39) or paclitaxel (n = 48), 3 to 24 months prior to assessme
Abstract by Jeremy Chung Bo Chiang; David Goldstein; Azadeh Tavakoli; Terry Trinh; Jacob Klisser; Craig R. Lewis; Michael Friedlander; Thomas J. Naduvilath, Scientific Reports (2021) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1038/s41598-021-02439-0