Macrophage numbers in the marginal area of sarcomas predict clinical prognosis
Michinobu Umakoshi; Akiko Nakamura; Hiroyuki Tsuchie; Zhuo Li; Yukitsugu Kudo-Asabe; Ken Miyabe; Yukinobu Ito; Makoto Yoshida · 2023 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Even when treated comprehensively by surgery, chemotherapy, and radiotherapy, soft-tissue sarcoma has an unfavorable outcome. Because soft-tissue sarcoma is rare, it is the subject of fewer clinicopathological studies, which are important for clarifying pathophysiology. Here, we examined tumor-associated macrophages in the intratumoral and marginal areas of sarcomas to increase our knowledge about the pathophysiology. Seventy-five sarcoma specimens (not limited to a single histological type), resected at our institution, were collected, and the number of CD68-, CD163-, and CD204-posit
Abstract by Michinobu Umakoshi; Akiko Nakamura; Hiroyuki Tsuchie; Zhuo Li; Yukitsugu Kudo-Asabe; Ken Miyabe; Yukinobu Ito; Makoto Yoshida, Scientific Reports (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1038/s41598-023-28024-1