Negative / Null Result ReportOpen accessMedicine· cited by 9

Reducing contrast media dosage for pulmonary embolism CTPA in PCD-CT: a comparative study of EID-CT and PCD-CT in the era of individualized protocolling

Lion Stammen; Eva J I Hoeijmakers; Thomas G. Flohr; Hester A. Gietema; Janneke Vandewall; Joachim Ernst Wildberger; Cécile R. L. P. N. Jeukens; Bibi Martens · 2025 · European Radiology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

OBJECTIVES: To evaluate diagnostic image quality (IQ) for pulmonary embolism detection in photon-counting detector CT (PCD-CT) with significantly reduced contrast media (CM) dose vs conventional energy-integrating detector CT (EID-CT), using optimized and individualized CM protocols. MATERIALS AND METHODS: Consecutive CT pulmonary angiography (CTPA) scans performed on the EID-CT (Jan 2024-Mar 2024) with an individualized kilovoltage (kV) and total body weight (TBW) adapted CM protocol, and on the PCD-CT (Aug 2023-Feb 2024) with a TBW adapted CM protocol matching the 70 kV EID-CT protocol, were

Abstract by Lion Stammen; Eva J I Hoeijmakers; Thomas G. Flohr; Hester A. Gietema; Janneke Vandewall; Joachim Ernst Wildberger; Cécile R. L. P. N. Jeukens; Bibi Martens, European Radiology (2025) — licensed CC BY 4.0.

Read the full paper (open access)