Biomarkers for advancing diagnosis and prognosis in stroke
Steffen Tiedt; Alejandro Bustamante; Alan Cameron; Pol Camps-Renom; Gerrit M Grosse; Johanna Ospel; Bastian Volbers; Heinrich J. Audebert · 2026 · The Lancet Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The complexity and incomplete understanding of the pathophysiology of stroke poses substantial challenges to personalised medicine and the development of novel therapies, as reflected in the neutral results of many randomised trials. Current clinical algorithms lack the precision to diagnose stroke before hospital admission, predict disease progression and recovery, or assess recurrence risk. Biomarkers are urgently needed, yet the absence of a robust evidence base hinders their clinical translation. To lay the groundwork for addressing this knowledge gap, an international multidisciplinary pa
Abstract by Steffen Tiedt; Alejandro Bustamante; Alan Cameron; Pol Camps-Renom; Gerrit M Grosse; Johanna Ospel; Bastian Volbers; Heinrich J. Audebert, The Lancet Neurology (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/s1474-4422(25)00480-6