TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
NiCole A. Finch; Minerva M. Carrasquillo; Matthew Baker; Nicola J. Rutherford; Giovanni Coppola; Mariely DeJesus‐Hernandez; Richard Crook; T. Hunter · 2010 · Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVES: To determine whether TMEM106B single nucleotide polymorphisms (SNPs) are associated with frontotemporal lobar degeneration (FTLD) in patients with and without mutations in progranulin (GRN) and to determine whether TMEM106B…
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Metadata source: OpenAlex · DOI 10.1212/wnl.0b013e31820a0e3b