Negative / Null Result ReportOpen accessMedicine

Interleukin-1β (IL-1β) C-511T polymorphism is associated with susceptibility to coronary artery disease in type 2 diabetic patients

Lijing Ma; Heng Su; Yan Wang; Yikun Zhou; Zhuang Kang; Ying Xu; Jie Gao · 2020 · European Journal of Inflammation

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Variants of the interleukin-1β (IL-1β) gene have been associated with type 2 diabetes (T2D) and coronary artery diseases (CAD). However, association of IL-1β polymorphisms with diabetic patients having CAD clinical manifestation has not been studied yet. In this study, we aim to decipher the role of IL-1β common promoter variants with susceptibility/resistance to development of CAD in T2D patients. T2D patients with (n = 134) or without CAD (n = 533) were enrolled. A total of 513 essentially healthy individuals from the same population were included in this study as control. Plasma levels of I

Abstract by Lijing Ma; Heng Su; Yan Wang; Yikun Zhou; Zhuang Kang; Ying Xu; Jie Gao, European Journal of Inflammation (2020) — licensed CC BY 4.0.

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