Zero-shot deep learning with multi-objective optimization improves thermostability of zearalenone hydrolase and xylanase.
Wu F; Wu R; Chen L; Chen Q; Liu H · 2026 · New biotechnology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Enhancing enzyme thermostability is crucial for industrial applications requiring robust performance under extreme conditions. Structure-based protein design models excel at improving thermal stability but often compromise enzymatic…
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Metadata source: Europe PMC · DOI 10.1016/j.nbt.2026.01.009