e-ISSN: Pending
Failed Experiment ReportOpen accessMedicine

Inhibition of p38α MAPK increases short-term astrocyte reactivity: the exploratory VIP trial in early Alzheimer's disease.

Gouilly D; Da-Costa A; Vrillon A; Pistono A; Goubeaud M; Bertrand E; Germain J; Ainaoui N · 2025 · Journal of neuroinflammation

WASTE classifies this as Failed Experiment Report · AI classification, approximate

An experimental approach did not work as intended — learn what to avoid before investing the same effort.

Abstract (excerpt)

BACKGROUND: Neuro-inflammation is an early mechanistic target in Alzheimer’s disease (AD). However, the effect of anti-inflammatory drugs on biomarkers of neuro-inflammation has yet to be described. Biomarkers of neuro-inflammation showed…

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Metadata source: Europe PMC · DOI 10.1186/s12974-025-03625-x