Circulating inflammatory biomarkers and risk of intracranial aneurysm: a Mendelian randomization study
Jianxun Fang; Yuze Cao; Jun Ni · 2024 · European Journal of Medical Research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Intracranial aneurysm (IA) accounts for a substantial source of non-traumatic subarachnoid hemorrhage, with inflammation postulated as a potential factor in its pathogenesis. The present study aims at evaluating the association between circulating inflammatory cytokines and risk of IA under a bidirectional two-sample Mendelian randomization (MR) design. Methods For primary analysis, summary statistics of inflammatory regulators was obtained from a genome-wide association study (GWAS) comprising 8293 Finnish participants. Summary data of IA were extracted from a GWAS which c
Abstract by Jianxun Fang; Yuze Cao; Jun Ni, European Journal of Medical Research (2024) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s40001-023-01609-2