Identification of Susceptibility Genes for Peritoneal, Ovarian, and Deep Infiltrating Endometriosis Using a Pooled Sample-Based Genome-Wide Association Study
Bruno Borghese; Jörg Tost; Magalie de Surville; Florence Busato; Frank Letourneur; F. Mondon; Daniel Vaiman; Charles Chapron · 2015 · BioMed Research International
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Characterizing genetic contributions to endometriosis might help to shorten the time to diagnosis, especially in the most severe forms, but represents a challenge. Previous genome-wide association studies (GWAS) made no distinction between peritoneal endometriosis (SUP), endometrioma (OMA), and deep infiltrating endometriosis (DIE). We therefore conducted a pooled sample-based GWAS and distinguished histologically confirmed endometriosis subtypes. We performed an initial discovery step on 10-individual pools (two pools per condition). After quality control filtering, a Monte-Carlo simulation w
Abstract by Bruno Borghese; Jörg Tost; Magalie de Surville; Florence Busato; Frank Letourneur; F. Mondon; Daniel Vaiman; Charles Chapron, BioMed Research International (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1155/2015/461024