Gas Chromatography–Sensor System Aids Diagnosis of Inflammatory Bowel Disease, and Separates Crohn’s from Ulcerative Colitis, in Children
Rachael Slater; Kukatharmini Tharmaratnam; Salma Belnour; Marcus Karl‐Heinz Auth; Rafeeq Muhammed; Christine Spray; Duolao Wang; Ben de Lacy Costello · 2024 · Sensors
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
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Abstract
The diagnosis of inflammatory bowel disease (IBD) in children and the need to distinguish between subtypes (Crohn's disease (CD) and ulcerative colitis (UC)) requires lengthy investigative and invasive procedures. Non-invasive, rapid, and cost-effective tests to support these diagnoses are needed. Faecal volatile organic compounds (VOCs) are distinctive in IBD. VOC profiles can be rapidly determined using a gas chromatography-sensor device (OdoReader©). In an inception-cohort of children presenting with suspected IBD, we directly compared the diagnostic fidelity of faecal calprotectin (FCP, a
Abstract by Rachael Slater; Kukatharmini Tharmaratnam; Salma Belnour; Marcus Karl‐Heinz Auth; Rafeeq Muhammed; Christine Spray; Duolao Wang; Ben de Lacy Costello, Sensors (2024) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/s24155079