Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos
Tamar Sofer; Leslie S. Emery; Deepti Jain; Alicia M. Ellis; Cathy C. Laurie; Matthew Allison; Jiwon Lee; Nuzulul Kurniansyah · 2019 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Lower extremity peripheral artery disease (PAD) burden differs by race/ethnicity. Although familial aggregation and heritability studies suggest a genetic basis, little is known about the genetic susceptibility to PAD, especially in non-European descent populations. Genome-wide association studies (GWAS) of the ankle brachial index (ABI) and PAD (defined as an ABI < 0.90) have not been conducted in Hispanics/Latinos. We performed a GWAS of PAD and the ABI in 7,589 participants aged >45 years from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). We also performed
Abstract by Tamar Sofer; Leslie S. Emery; Deepti Jain; Alicia M. Ellis; Cathy C. Laurie; Matthew Allison; Jiwon Lee; Nuzulul Kurniansyah, Scientific Reports (2019) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41598-019-47928-5