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Negative / Null Result ReportOpen accessMedicine· cited by 32

Management of Primary Biliary Cholangitis: Current Treatment and Future Perspectives

Romelia Barba Bernal; Bryan W. Ferrigno; Esli Medina Morales; Cristina Castro; Daniela Goyes; Hirsh D. Trivedi; Vilas Patwardhan; Alan Bonder · 2023 · The Turkish Journal of Gastroenterology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Primary biliary cholangitis is an autoimmune cholestatic liver disease characterized by progressive destruction of bile ducts, which can ultimately progress to chronic liver disease and cirrhosis. Ursodeoxycholic acid and obeticholic acid are the only 2 Food and Drug Administration (FDA)-approved medications for primary biliary cholangitis. Unfortunately, up to 40% of patients with primary biliary cholangitis have an incomplete response to ursodeoxycholic acid, warranting an essential need for additional therapeutics. Peroxisome proliferator-activated receptor agonists have shown promising dat

Abstract by Romelia Barba Bernal; Bryan W. Ferrigno; Esli Medina Morales; Cristina Castro; Daniela Goyes; Hirsh D. Trivedi; Vilas Patwardhan; Alan Bonder, The Turkish Journal of Gastroenterology (2023) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.5152/tjg.2023.22239