Expression of DNA Gyrase at mRNA Levels and Antibacterial Effect of FluoroquinoloneDerived Compounds on Two Antibiotic Resistant Bacteria; Staphylococcus aureus and Enterococcus faecalis
Shokrollah Assar; Ali Darehkordi; Mohammad Moradi; Mahmood Sheikh Fathollahi; Soudeh Khanamani Falahati Pour; Gholamhossein Hassanshahi · 2019 · Journal of Clinical and Diagnostic Research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Introduction: Fluoroquinolones are a form of antibiotics capable of influencing DNA Gyrase of bacteria. Any alteration in the structure of current fluoroquinolone antibacterials may provide a better effect on the growth inhibition of bacteria. Aim: To assess the probable anti-bacterial activity of two fluoroquinolone derivatives on Staphylococcus aureus (S.aureus) and Enterococcus faecalis (E. faecalis). Materials and Methods: The inhibitory effect of two synthetic derivatives of fluoroquinolones, N-4-methyl (phenyl) -2,2,2- trifluoroacetimidoyl ciprofloxacin (C1), and N-4-methyl (phenyl) -2,2
Abstract by Shokrollah Assar; Ali Darehkordi; Mohammad Moradi; Mahmood Sheikh Fathollahi; Soudeh Khanamani Falahati Pour; Gholamhossein Hassanshahi, Journal of Clinical and Diagnostic Research (2019) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.7860/jcdr/2019/42907.13332