Detecting Corticospinal Tract Impairment in Tumor Patients With Fiber Density and Tensor-Based Metrics
Lucius S. Fekonja; Ziqian Wang; Dogu Baran Aydogan; Timo Roine; Melina Engelhardt; Felix R. Dreyer; Peter Vajkoczy; Thomas Picht · 2021 · Frontiers in Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Tumors infiltrating the motor system lead to significant disability, often caused by corticospinal tract injury. The delineation of the healthy-pathological white matter (WM) interface area, for which diffusion magnetic resonance imaging (dMRI) has shown promising potential, may improve treatment outcome. However, up to 90% of white matter (WM) voxels include multiple fiber populations, which cannot be correctly described with traditional metrics such as fractional anisotropy (FA) or apparent diffusion coefficient (ADC). Here, we used a novel fixel-based along-tract analysis consisting of cons
Abstract by Lucius S. Fekonja; Ziqian Wang; Dogu Baran Aydogan; Timo Roine; Melina Engelhardt; Felix R. Dreyer; Peter Vajkoczy; Thomas Picht, Frontiers in Oncology (2021) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fonc.2020.622358