Lamotrigine serum concentrations as longitudinal biomarkers for seizure risk prediction in pregnant women with epilepsy: a secondary analysis of the EMPiRE study.
Allotey J; Junaid F; Peréz T; Rolle V; Pardo MDC; Zamora J; Thangaratinam S · 2026 · BMJ neurology open
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Serum lamotrigine concentrations fall during pregnancy, and therapeutic drug monitoring is often used to guide dose adjustment. We do not know whether serial antenatal measurements improve prediction of seizure risk in pregnant…
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Metadata source: Europe PMC · DOI 10.1136/bmjno-2026-001547