CX3CR1<sup>+</sup> synovial macrophages accumulate in the joint during experimental hemophilic arthropathy but are not required for acute synovitis.
Lawrence AG; Murangi T; Chevalier A; Ivers D; O'Donnell JS; Turecek PL; Fallon PG · 2026 · Journal of thrombosis and haemostasis : JTH
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Hemophilic arthropathy (HA) is a chronic joint disease caused by repeated joint bleeding in patients with hemophilia, leading to joint degeneration despite prophylactic treatment. The CX3CL1 (fractalkine)-CX3CR1 chemokine axis…
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Metadata source: Europe PMC · DOI 10.1016/j.jtha.2026.04.035