Safety and tolerability of switching to bictegravir/emtricitabine/tenofovir alafenamide versus continuing dolutegravir/lamivudine in people living with HIV with neuropsychiatric comorbidities: Week 24 and 48 results from the Management of INSTI-associated Neuropsychiatric Disorders (MIND) clinical trial.
Perez-Valero I; Corona Mata D; Crussells Canales MJ; Velasco Arribas M; Mican Rivera R; Ryan P; Navarrete-Lorite MN; Tiraboschi J · 2026 · International journal of antimicrobial agents
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Objective To evaluate if switching from dolutegravir/lamivudine (DTG/3TC) to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) improves neuropsychiatric tolerability in suppressed adults with stable neuropsychiatric…
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Metadata source: Europe PMC · DOI 10.1016/j.ijantimicag.2026.107825