Loss of p21 does not protect against premature ovarian insufficiency caused by alkylating agents.
Lu X; Han Y; Song J; Wan Q; Liu P; Chen L; Wang Y; Xue P · 2025 · Frontiers in endocrinology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Recent studies have focused on investigating the role of cellular senescence in ovarian aging. Targeting cellular senescence has been proposed as a potential strategy to improve ovarian aging. p16 and p21 are classical molecules…
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Metadata source: Europe PMC · DOI 10.3389/fendo.2025.1616965