Negative / Null Result ReportOpen accessMedicine· cited by 97

ITPKC Single Nucleotide Polymorphism Associated with the Kawasaki Disease in a Taiwanese Population

Ho‐Chang Kuo; Kuender D. Yang; Suh‐Hang Hank Juo; Chi‐Di Liang; Wei-Chiao Chen; Yu‐Shiuan Wang; Chih‐Hung Lee; Edward Hsi · 2011 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

The finding, in one line

“In this study, no significant association was noted for the ITPKC polymorphism (rs28493229) between the controls and KD patients, although the CC genotype was overrepresented.”

Abstract

Kawasaki disease (KD) is characterized by systemic vasculitis with unknown etiology. Previous studies from Japan indicated that a gene polymorphism of ITPKC (rs28493229) is responsible for susceptibility to KD. We collected DNA samples from 1,531 Taiwanese subjects (341 KD patients and 1,190 controls) for genotyping ITPKC. In this study, no significant association was noted for the ITPKC polymorphism (rs28493229) between the controls and KD patients, although the CC genotype was overrepresented. We further combined our data with previously published case/control KD studies in the Taiwanese pop

Abstract by Ho‐Chang Kuo; Kuender D. Yang; Suh‐Hang Hank Juo; Chi‐Di Liang; Wei-Chiao Chen; Yu‐Shiuan Wang; Chih‐Hung Lee; Edward Hsi, PLoS ONE (2011) — licensed CC BY 4.0.

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