Effect of calcium vs. placebo on long-term outcomes in patients with out-of-hospital cardiac arrest
Mikael Fink Vallentin; Asger Granfeldt; Carsten Meilandt; Amalie Ling Povlsen; Birthe Sindberg; Mathias J. Holmberg; Bo Nees Iversen; Rikke Mærkedahl · 2022 · Resuscitation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
OBJECTIVE: The Calcium for Out-of-hospital Cardiac Arrest (COCA) trial was a randomized, placebo-controlled, double-blind trial of calcium for out-of-hospital cardiac arrest. The primary and secondary outcomes have been reported previously. This article describes the long-term outcomes of the trial. METHODS: Patients aged ≥18 years were included if they had a non-traumatic out-of-hospital cardiac arrest during which they received adrenaline. The trial drug consisted of calcium chloride (5 mmol) or saline placebo given after the first dose of adrenaline and again after the second dose of adrena
Abstract by Mikael Fink Vallentin; Asger Granfeldt; Carsten Meilandt; Amalie Ling Povlsen; Birthe Sindberg; Mathias J. Holmberg; Bo Nees Iversen; Rikke Mærkedahl, Resuscitation (2022) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.resuscitation.2022.07.034