e-ISSN: Pending
Negative / Null Result ReportMedicine

Frontline Pembrolizumab or Methotrexate in Elderly, Frail, or Cisplatin-Ineligible Patients with Relapsed or Metastatic Squamous Cell Carcinoma of the Head and Neck: Results of the Randomized Phase 2 Study ELDORANDO (AIO-KHT-0115).

Klinghammer K; Graeven U; Ivanyi P; Dietz A; Hahn D; Hackenberg S; Kasper S; Haderlein M · 2026 · Oncology research and treatment

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Introduction Elderly, frail, or cisplatin-ineligible patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M HNSCC) have a poor prognosis. To date, no standard of care has been defined for this population.…

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Metadata source: Europe PMC · DOI 10.1159/000549947