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Negative / Null Result ReportOpen accessMedicine· cited by 61

The Era of Antimicrobial Peptides: Use of Hepcidins to Prevent or Treat Bacterial Infections and Iron Disorders

Carolina Barroso; Pedro Carvalho; M.C. Nunes; Giovani Sampaio Gonçalves; Pedro Rodrigues; João V. Neves · 2021 · Frontiers in Immunology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

The current treatments applied in aquaculture to limit disease dissemination are mostly based on the use of antibiotics, either as prophylactic or therapeutic agents, with vaccines being available for a limited number of fish species and pathogens. Antimicrobial peptides are considered as promising novel substances to be used in aquaculture, due to their antimicrobial and immunomodulatory activities. Hepcidin, the major iron metabolism regulator, is found as a single gene in most mammals, but in certain fish species, including the European sea bass ( Dicentrarchus labrax ), two different hepci

Abstract by Carolina Barroso; Pedro Carvalho; M.C. Nunes; Giovani Sampaio Gonçalves; Pedro Rodrigues; João V. Neves, Frontiers in Immunology (2021) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.3389/fimmu.2021.754437