Negative / Null Result ReportOpen accessMedicine· cited by 22

Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index

Kazuyuki Uehara; Takashi Sasayama; Daisuke Miyawaki; Hideki Nishimura; Kenji Yoshida; Yoshiaki Okamoto; Naritoshi Mukumoto; Hiroaki Akasaka · 2012 · Radiation Oncology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BACKGROUND: The purpose of the present study was to analyze the recurrence pattern of high-grade glioma treated with a multimodal treatment approach and to evaluate whether the MIB-1 labeling index (LI) could be a useful marker for predicting the pattern of failure in glioblastoma (GB). METHODS AND MATERIALS: We evaluated histologically confirmed 131 patients with either anaplastic astrocytoma (AA) or GB. A median dose was 60 Gy. Concomitant and adjuvant chemotherapy were administered to 111 patients. MIB-1 LI was assessed by immunohistochemistry. Recurrence patterns were categorized according

Abstract by Kazuyuki Uehara; Takashi Sasayama; Daisuke Miyawaki; Hideki Nishimura; Kenji Yoshida; Yoshiaki Okamoto; Naritoshi Mukumoto; Hiroaki Akasaka, Radiation Oncology (2012) — licensed CC BY 4.0.

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