e-ISSN: Pending
Negative / Null Result ReportMedicine

Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial.

Folkert IW; Mehran R; Sun R; Morris VK; Overman MJ; Kee B; Antonoff MB; Tzeng CW · 2026 · Annals of surgical oncology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Background Hepatectomy for isolated colorectal liver metastases is associated with 5 year overall survival (OS) of 58% and is accepted as standard of care. However, the role of liver resection with unresectable low-volume lung metastases…

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Metadata source: Europe PMC · DOI 10.1245/s10434-025-18854-w