Long-Term Survival and Differentiation of Human Neural Stem Cells in Nonhuman Primate Brain with no Immunosuppression
Sang‐Rae Lee; Hong J. Lee; Sang-Hoon Cha; Kang-Jin Jeong; Youngjeon Lee; Chang‐Yeop Jeon; Kyung Sik Yi; Inja Lim · 2015 · Cell Transplantation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Cellular fate of human neural stem cells (hNSCs) transplanted in the brain of nonhuman primates (NHPs) with no immunosuppression was determined at 22 and 24 months posttransplantation (PTx) regarding survival, differentiation, and tumorigenesis. Survival of hNSCs labeled with magnetic nanoparticles was successfully detected around injection sites in the brain at 22 months PTx by MRI. Histological examination of brain sections with H&E and Prussian blue staining at 24 months revealed that most of the grafted hNSCs were found located along the injection tract. Grafted hNSCs were found to differe
Abstract by Sang‐Rae Lee; Hong J. Lee; Sang-Hoon Cha; Kang-Jin Jeong; Youngjeon Lee; Chang‐Yeop Jeon; Kyung Sik Yi; Inja Lim, Cell Transplantation (2015) — licensed CC BY-SA 4.0.
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Metadata source: OpenAlex · DOI 10.3727/096368914x678526