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Negative / Null Result ReportOpen accessMedicine· cited by 245

Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma

Brian A. Walker; Christopher P. Wardell; Lorenzo Melchor; Sanna Hulkki; Nicola Potter; David C. Johnson; Kerry Fenwick; Iwanka Kozarewa · 2012 · Blood

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

We have used whole exome sequencing to compare a group of presentation t(4;14) with t(11;14) cases of myeloma to define the mutational landscape. Each case was characterized by a median of 24.5 exonic nonsynonymous single-nucleotide…

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Metadata source: OpenAlex · DOI 10.1182/blood-2012-03-412981