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Negative / Null Result ReportOpen accessAnesthesiology

Comparing the effects of magnesium sulfate and lidocaine spray on hemodynamic changes caused by laryngoscopy and tracheal intubation: a randomized clinical trial

Marzieh khalaji; Mohadese Babaie; Fatemeh Bayat; Mehdi Rezaee; Banafsheh Mashak · 2025 · BMC Anesthesiology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Abstract Aim This study aims at comparing the impact of Magnesium Sulfate and Lidocaine sprays on hemodynamic changes after laryngoscopy and tracheal intubation. Design This double-blind clinical trial (code IRCT20230719058846N1) was conducted on the patients undergoing elective surgery in the city of Karaj. Methods A total of 100 patients, aged 18 to 40 years and classified as ASA I or II, who were candidates for elective surgery, were randomly assigned to two equal groups. Prior to intubation, patients received lidocaine spray (5 puffs of Lidocaine 10%) in one group, and magnesium sulfate sp

Abstract by Marzieh khalaji; Mohadese Babaie; Fatemeh Bayat; Mehdi Rezaee; Banafsheh Mashak, BMC Anesthesiology (2025) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1186/s12871-025-02962-x