Cognitive Go/No-Go decision-making criteria in Alzheimer's disease drug development.
Wessels AM; Edgar CJ; Nathan PJ; Siemers ER; Maruff P; Harrison J · 2021 · Drug discovery today
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
Go/No-Go decision making in early phase clinical trials is challenging for drug developers working in Alzheimer's disease. Recent negative trial results have been attributed to a lack of efficacy and important safety concerns. Furthermore,…
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Metadata source: Europe PMC · DOI 10.1016/j.drudis.2021.01.012